Browse result page of B3Pdb

The total number entries retrieved from this search are 7, scroll left/right for detailed information.
B3pdbIDPEPTIDE NAMEPEPTIDE SEQUENCE (1-letter)PEPTIDE SEQUENCE (3-letter)N-TERMINAL MODIFICATIONC-TERMINAL MODIFICATION CHEMICAL MODIFICATIONPEPTIDE LENGTHPEPTIDE CONFORMATIONPEPTIDE NATURESOURCE/ORIGIN OF PEPTIDESMILESCELL LINEIn vitro CONCENTRATIONIn vitro METHODIn vitro RESULTANIMAL MODELIn vivo CONCENTRATIONIn vivo MODE OF DELIVERYIn vivo METHODIn vivo RESULTACTIONTRANSPORT TYPESUBCELLULAR LOCALISATIONCOMBINATIONPHYSICAL CONDITIONRESPONSERESULTLABELPMID
b3pdb_0147Goldnanoparticle conTHRPPMWSPVWPThrHisArgProProMetTrpSerProValTrpProNANAConjugated with CLPFFD goldnaNAparticle12LinearCationicChemically synthesizedNANANANANAAdult Sprague-Dawley rats1.86 mg/KgIntraperitonealInstrumental neutron activation analysis and Nissl stainingConjugate was found to cross blodd brain barrier; does not effect mice survival; no toxicity as meas NA NA NA NA Alzheimer NA NA NA 22795856
b3pdb_0150MMP-2200Y-D-TGFLS(β-O-Glc)-CONH2Tyr-D-Thr-Gly-Phe-Leu-Ser(β-O-Glc)-CONH2NANAGlycosylated serine residue6LinearNAChemically synthesizedNANANANANAAdult Sprague-Dawley rats10mg/KgIntraperitonealMicrodialysis analysis and LCMS analysisSignificant amount of peptide crosses blood brain barrier after 12 minute and remain stable up to 80 Shows potent analgesic behaviour NA NA NA Parkinson Stability/half life 80 minute NA 23127847
b3pdb_0151MPEG-PCL-TatNANAAddition of MPEG and ploygalactolactoneNAAddition of MPEG and PCLNALinearNAChemically synthesizedNANANANANAAdult Sprague-Dawley rats100 microliterIntravenous Fluoroscent screening by FITC labbled peptide maass in brain tissue0.5% fluoroscence observed in brain tissue NA NA NA NA NA NA NA NA 23992922
b3pdb_0152MPEG-PCL-TatNANAAddition of MPEG and ploygalactolactoneNAAddition of MPEG and PCLNALinearNAChemically synthesizedNANANANANAAdult Sprague-Dawley rats10 microliterIntranasalFluoroscent screening by FITC labbled peptide maass in brain tissue2.5% fluoroscence observed in brain tissue NA NA NA NA NA NA NA NA 23992922
b3pdb_0292CTAPNAD-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2NANANANACyclicNANANANANANANAAdult Sprague-Dawley ratsNAin situ brain perfusion technique coupled to high performance liquid chromatographic analysis.NAT1/2 > 500 min NA NA NA NA NA half life, serum T1/2 > 500 min NA 8996221
b3pdb_0362opioid glycopeptide Y-D-TGFLS(β-O-Glc)-CONH2Tyr-D-Thr-Gly-Phe-Leu-Ser(β-O-Glc)-CONH2NANANA6LinearNANANANANANAAdult Sprague-Dawley ratsNANANAHigh penetration NA NA NA NA NA NA NA NA 23127847
b3pdb_0372HemopressinNANANANANANALinearNANANANANANAAdult Sprague-Dawley ratsNANANANA NA NA NA NA NA NA NA NA 23542442